Aromatic Synthesis (1) – “Order Of Operations”
When planning a synthesis of simple aromatic compounds, it’s not enough to pick the right reactions. You also have to put them in the right
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Aromatic Synthesis (2) – Polarity Reversal
In planning the synthesis of simple aromatic compounds, it’s vital to know some tricks for changing ortho-, para- directors into meta- directors, and vice versa! Here we go
Read moreSynthesis (7): Reaction Map of Benzene and Related Aromatic Compounds
Reactions of Aromatic Compounds: A Reaction Map Let’s map out all of the reactions we’ve learned in this section on aromatic rings + substituents. The
Read moreSynthesis Using Grignard Reagents (1)
Here’s the bottom line for today’s post on solving synthesis problems involving Grignard reagents. Solving Synthesis Problems Involving Grignard Reagents Now that we’ve covered some
Read moreGrignard Reactions And Synthesis (2)
Here’s the summary for today’s post on synthesis incorporating Grignard reagents and oxidants. Converting an aldehyde into a tertiary alcohol can be performed if we
Read moreWilliamson Ether Synthesis: Planning
In the last post we introduced the Williamson ether synthesis, one of the most straightforward ways we know of to make an ether. If you’ve been
Read moreEther Synthesis Via Alcohols And Acid
Last post I got a little ahead of myself. I was all excited about getting into the reactions of ethers, and forgot that there’s one
Read moreThe Organic Chemistry Behind “The Pill”
The Most Interesting Man In The World passed away the other week. No, not THAT guy. He’s just an actor. The OTHER guy. The OTHER
Read moreThe 2 Most Important Reactions of Alkynes
With the series of posts on alkenes in the can, let’s move on and talk about a closely related functional group that shares many reactions
Read moreIntroduction To Synthesis
By this point we’ve gone over all the major classes of reaction covered in many typical first semester organic chemistry courses.: acid base, substitution, elimination,
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