Rearrangement Reactions (1) – Hydride Shifts
For nucleophilic substitution, the pattern of bonds that form and break is pretty straightforward. You break C-(leaving group) and you form C-(nucleophile). A straight swap. But
Read morenucleophilic substitution
Introduction to Nucleophilic Substitution Reactions
Following up on the 4 most important patters of reactions in Org 1, and introduction to acid-base reactions, here’s the second major pattern. It’s called
Read moreThe SN2 Mechanism
Having gone through the two different types of substitution reactions, and talked about nucleophiles and electrophiles, we’re finally in a position to reveal the mechanism
Read moreThe 4 Major Classes of Reactions in Org 1
At least 80% of the reactions you will learn in Org 1 fall into one of these 4 categories. The sooner you can get into the habit of recognizing bond formation and breakage the better off you will be.
Read moreWhat makes a good leaving group?
A leaving group is a nucleophile acting in reverse; it accepts a lone pair as the bond between it and its neighbor (usually carbon for
Read moreSteric Hindrance is Like a Fat Goalie
Sportswriter Todd Gallagher asked a question that every hockey fan has probably asked at one point. “Could a morbidly obese goaltender succeed in the NHL?”
Read more