Electrophilic Aromatic Substitution: Introduction
A key reaction of aromatic compounds is electrophilic aromatic substitution, where a C-H bond is broken and a new C-E bond (E being an electrophilic
Read moreA key reaction of aromatic compounds is electrophilic aromatic substitution, where a C-H bond is broken and a new C-E bond (E being an electrophilic
Read moreToday’s post is on the Friedel-Crafts alkylation and acylation reactions. Quick summary: This is the third in a series of three posts on the key
Read moreWe explore the intramolecular Friedel-Crafts reaction in this post. But first, a very quick refresher on intramolecular reactions in general. Quick Recap: Intramolecular Reactions Can
Read moreIn this post we go through 4 ways of reducing C=O to CH2 including: The Wolff-Kishner reaction The Clemmensen reduction Catalytic hydrogenation Thioacetal formation and
Read moreWhen planning a synthesis of simple aromatic compounds, it’s not enough to pick the right reactions. You also have to put them in the right
Read moreIn planning the synthesis of simple aromatic compounds, it’s vital to know some tricks for changing ortho-, para- directors into meta- directors, and vice versa! Here we go
Read moreToday’s Reaction Friday is about the Friedel Crafts acylation of benzene and other aromatics, an important example of electrophilic aromatic substitution. One thing I forgot
Read moreZed Shaw teaches a course in writing Python called “Python the Hard Way“. Because the hard way is easier, he says. In the end, he’s
Read moreIn a blatant plug for the Reagent Guide, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org 2. Note: there’s
Read moreSo I bought a belt today (pleather, 75 cents at the Goodwill). and decided to show it off. This is me putting it together. This
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