The Hofmann Elimination
The Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi bonds]. [note] It proceeds through a concerted E2 mechanism. In contrast with
Read moreThe Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi bonds]. [note] It proceeds through a concerted E2 mechanism. In contrast with
Read moreThe “Cope Elimination” is a reaction where an amine is oxidized to an intermediate called an “N-oxide”, which, when heated, acts as the base in
Read moreThe previous four posts on acid-base, substitution, addition, and elimination covered the 4 main reactions in organic chemistry I. Now it’s time to go beyond
Read moreHere’s a summary of what we talk about in today’s post. Hydrohalic acids (HX) plus alcohols give substitution products… We just saw that treating an
Read moreHere’s what we talk about today: more eliminations of alcohols! Note that this reagent isn’t covered in all courses, but I’ll include it here for completeness’
Read moreIn previous series, we’ve discussed acid-base reactions, nucleophilic substitution reactions, and elimination reactions. These represent three of the four most important reaction types in a
Read moreHaving gone through the SN1, the SN2, the E1, and the E2 reactions in turn, we can now say the following: Both substitution reactions and elimination
Read moreFor the previous posts in Adam’s series on the SN1/SN2/E1/E2, see Part 1 Part 2 Part 3. – James Three And A Half Steps To
Read moreThe second in a series of guest posts on SN1/SN2/E1/E2 by Chemistry Blog author and “instructor of organic chemistry at a small Midwestern liberal arts
Read moreWe’ve gone through elimination reactions before – treatment of alkyl halides with base gives alkenes. Some time ago we discussed elimination reactions here. Elimination reactions
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