The Hofmann Elimination
The Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi bonds]. [note] It proceeds through a concerted E2 mechanism. In contrast with
Read moreThe Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi bonds]. [note] It proceeds through a concerted E2 mechanism. In contrast with
Read moreThe “Cope Elimination” is a reaction where an amine is oxidized to an intermediate called an “N-oxide”, which, when heated, acts as the base in
Read moreIn the last post, we discussed the acid-base properties of alcohols. Two posts ago, we said that acid-base reactions are often used to “set up”
Read moreToday we’re going to talk about a different way of making alcohols into good leaving groups – by turning them into tosylates and mesylates (“organosulfonates”). Here’s a
Read moreHere’s what we talk about today: more eliminations of alcohols! Note that this reagent isn’t covered in all courses, but I’ll include it here for completeness’
Read moreHaving gone through the SN1, the SN2, the E1, and the E2 reactions in turn, we can now say the following: Both substitution reactions and elimination
Read morePart 6 of a 6 part series. Previous posts in the series: 1 2 3 4 5 – James 3 ½ Steps To Any SN1/SN2/E1/E2 Reaction: Wrap
Read moreFor the previous posts in Adam’s series on the SN1/SN2/E1/E2 decision, see Part 1 Part 2 Part 3 and Part 4 – James Three And A Half Steps To Any
Read moreFor the previous posts in Adam’s series on the SN1/SN2/E1/E2, see Part 1 Part 2 Part 3. – James Three And A Half Steps To
Read moreFollowing from Adam’s last guest post on the SN1/SN2/E1/E2 (“The Leaving Group“) here is part 3 of the series! – James Step One: What is
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