The Williamson Ether Synthesis
In the last post, we discussed the acid-base properties of alcohols. Two posts ago, we said that acid-base reactions are often used to “set up”
Read morebase
Guest Post On SN1/SN2/E1/E2 (6): Wrapup
Part 6 of a 6 part series. Previous posts in the series: 1 2 3 4 5 – James 3 ½ Steps To Any SN1/SN2/E1/E2 Reaction: Wrap
Read moreWrapup: The Quick N’ Dirty Guide To SN1/SN2/E1/E2
The previous several posts dealt with an approach to solving substitution and elimination problems that can only be described as a Quick N’ Dirty Guide
Read moreWalkthrough of Elimination Reactions (1)
As you’ve probably noticed by now, organic chemistry is a lot different from physics. When we’re looking to predict what reaction might occur in a
Read moreElimination Reactions Are Favored By Heat
A few posts back we saw how elimination reactions are often in competition with substitution reactions. ow do we know when one reaction pathway is
Read moreThe E1 Reaction
Last time in this walkthrough on elimination reactions, we talked about two types of elimination reactions. In this post, we’re going to dig a little bit
Read moreThe E2 Mechanism
Having gone through the E1 mechanism for elimination reactions, we’ve accounted for one way in which elimination reactions can occur. However, there’s still another set
Read moreComparing the E1 and E2 Reactions
Now that we’ve gone through the mechanisms of the E1 and E2 reactions, let’s take a moment to look at them side by side and
Read moreThe E2 Reaction and Cyclohexane Rings
Last time we compared the E1 and E2 reactions and mentioned one of the key differences was the stereochemistry of the E2 reaction. Remember that
Read moreBulky Bases in Elimination Reactions
We’ve recently talked about Zaitsev’s rule in elimination reactions, and how the transition state leading to the more substituted alkene is lower in energy. The
Read more