Summary Sheet: Functional Groups
I thought it would be good to make a summary sheet based on functional groups, so here one is: Functional Group Summary Sheet (PDF) You
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Why the SN2 Reaction Is Powerful
Having gone through the mechanism of the SN2 reaction, let’s take a second and look at why it might be useful. In nucleophilic substitution reactions,
Read moreReaction Friday – Fischer Esterification
The Fischer esterification is one of the most important reactions of carboxylic acids. Treatment of carboxylic acids with an alcohol in the presence of acid
Read moreReaction Friday: Formation of Acetals from Ketones
Today’s video is about the formation of acetals from aldehydes and ketones, an important method for the protection of the carbonyl group. One thing I
Read moreReaction Friday: Addition of Grignard Reagents to Ketones
Grignard reagents are very useful carbon-based nucleophiles and will readily form carbon-carbon bonds with carbonyl compounds. Here the reaction of Grignard reagents with ketones is
Read moreReagent Friday: Thionyl Chloride (SOCl2)
In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org
Read moreReagent Friday: LiAlH[Ot-Bu]3
In a blatant plug for the Reagent Guide and the Reagents App for iPhone, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org
Read moreOxidation Ladders
Once you get a handle on oxidations and reductions, you might start to notice that with some molecules these reactions can proceed in sequences. For
Read moreSynthesis (6) – Reactions of Alcohols
The Alcohol Reaction Map Having now finished (at long last) covering the key reactions of alcohols, let’s stop to put everything in perspective. Over the
Read moreReagent Friday: TsCl (p-toluenesulfonyl chloride) and MsCl (methanesulfonyl chloride)
In a blatant plug for the Reagent Guide, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org 2. A friend
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