What’s An Organometallic?
Quick summary for today – the first in a new series on organometallic compounds: Previously on MOC we’ve discussed how important dipoles are in determining the reactivity
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Synthesis of Grignard and Organolithium Reagents
In the last post we introduced the concept of organometallic compounds – molecules where carbon is bound to a less electronegative atom such as Li,
Read moreOrganometallics Are Strong Bases
Last post we talked about how to make certain organometallics, specifically Grignard and organolithium reagents. One thing we saw is that they tend to be
Read moreReactions of Grignard Reagents
Here’s the summary for today’s post: So far in this series we’ve introduced organometallic compounds and said that their carbons tend to be nucleophilic. We’ve
Read moreProtecting Groups In Grignard Reactions
Now that we’ve gone over the most useful reactions of Grignard reagents – addition to epoxides, aldehydes, ketones, and esters – let’s go back to
Read moreSynthesis Using Grignard Reagents (1)
Here’s the bottom line for today’s post on solving synthesis problems involving Grignard reagents. Solving Synthesis Problems Involving Grignard Reagents Now that we’ve covered some
Read moreGrignard Reactions And Synthesis (2)
Here’s the summary for today’s post on synthesis incorporating Grignard reagents and oxidants. Converting an aldehyde into a tertiary alcohol can be performed if we
Read moreGilman Reagents (Organocuprates): How They’re Made
Here’s the summary for today’s post: Organometallics: What About The Rest Of The Periodic Table? In this whole series on organometallics so far has covered
Read moreGilman Reagents (Organocuprates): What They’re Used For
Last time we talked about how to make Gilman reagents (organocuprates). In this post, we’ll talk about what they’re actually used for. Here’s a summary
Read moreCommon Mistakes with Carbonyls: Carboxylic Acids… Are Acids!
Carboxylic acids… are acids. I know that seems obvious. But it’s a near certainty that students taking Org 2 for the first time will forget
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