Today, building on the previous 2-part series on mechanisms of anionic nucleophiles in carbonyl chemistry, I’m going to start looking at the reactions of the neutral nucleophiles: water, alcohols, amines, enols …
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Our New Book, "Practice Organic Mechanisms", Is OutPosted on: Mar 14, 2016
The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don't Belong In Most Posted on: Mar 10, 2016
Gilman Reagents (Organocuprates): What They're Used ForPosted on: Feb 05, 2016
Gilman Reagents (Organocuprates): How They're MadePosted on: Jan 29, 2016
Grignard Reactions And Synthesis (2)Posted on: Jan 19, 2016
said in Reagent Friday: Chromic Acid, H2CrO4 - The reaction is usually run in acetone or other organic solvent. Whether or not an aldehyde is water soluble wo... →
said in Conversion of carboxylic acids to esters using acid and alcohols (Fischer Esterification) - How about in the case of mevalonate forming a cyclic ester to become mevalolactone? Mevalonate is in its carboxyl... →
said in Imines and Enamines - Ah! This makes so much sense! Might I suggest the Learn 6 reactions for the price of one article be linked? ... →
said in The Heck, Suzuki, and Olefin Metathesis Reactions (And Why They Don’t Belong In Most Introductory Organic Chemistry Courses) - I completely agree with your analysis, and your conclusion that these reactions shouldn't be taught as a part... →
What Makes A Good Nucleophile?
Five Key Factors That Influence Acidity
3 Trends That Affect Boiling Points
Comparing the SN1 and SN2 Reactions
Polar Protic? Polar Aprotic? Nonpolar? All About Solvents