Ace Your Next Organic Chemistry Exam.

With these Downloadable PDF Study Guides

Our Study Guides

Amines

Basicity of Amines And pKaH

How do you measure the basicity of an amine? Case in point: what’s a stronger base: pyridine or piperidine? If you said piperidine, congratulations – it is

Read more

Nucleophilicity of Amines

Bonus Topic – Nucleophilicity Of Amines The relative nucleophilicity of amines doesn’t get a  lot of coverage (translation: doesn’t get tested) in many organic chemistry

Read more

Alkylation of Amines (Sucks)

Trends in the basicity of amines provide a classic example of why chemistry is so interesting; it’s deciphering the delicate trade-offs between various general factors

Read more

Reductive Amination

OK – so making amines through direct alkylation is generally not a great way to go. You could even say it’s crappy. So what’s the

Read more

The Gabriel Synthesis

We’ve seen previously that it’s hard to *usefully* build amines through the SN2 reaction, because once amines start reacting with alkyl halides, the products tend

Read more

Some Reactions of Azides

The azide ion (N3– ) is one of those chemical entities that just plain looks weird.  Three nitrogens in a row? check Two negative charges and a positive charge,

Read more

The Hofmann Elimination

The Hofmann Elimination is an elimination reaction of alkylammonium salts that forms C-C double bonds [pi bonds]. [note] It proceeds through a concerted E2 mechanism. In contrast with

Read more