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Organic Reagents

By James Ashenhurst

Reaction Friday: Formation of Acetals from Ketones

Last updated: March 27th, 2019

Today’s video is about the formation of acetals from aldehydes and ketones, an important method for the protection of the carbonyl group.

One thing I forgot to mention in the video is that the reaction is an equilibrium – choosing alcohol as the solvent ensures that the equilibrium will be driven towards formation of the acetal, whereas treatment of acetals in aqueous acid leads to re-formation of the carbonyl group.

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